Degradable fluorescent single-chain nanoparticles based on metathesis polymers.

Janin T OffenlochJohannes WillenbacherPavleta TzvetkovaCarolin HeilerHatice MutluChristopher Barner-Kowollik

Published in: Chemical communications (Cambridge, England) (2018)

We introduce the facile synthesis of fluorescent single-chain nanoparticles (SCNPs) based on chain-shattering acyclic diene metathesis (ADMET) polymers featuring self-immolative azobenzene motifs. An electrophilic alkoxyetherification is utilized to introduce the photoreactive moieties required for the subsequent chain collapse via UV-induced nitrile imine-mediated tetrazole-ene cycloaddition (NITEC).

Keyphrases

quantum dots
oxidative stress
stress induced