Head circumference as a useful surrogate for intracranial volume in older adults.
Tammy T HshiehMeaghan L FoxCyrus M KosarMichele CavallariCharles R G GuttmannDavid C AlsopEdward R MarcantonioEva M SchmittRichard N JonesSharon K InouyePublished in: International psychogeriatrics (2016)
Head circumference measurement was strongly correlated with MRI-derived ICV. Our study presents a simple method to approximate ICV among older patients, which may prove useful as a surrogate for cognitive reserve in large scale epidemiologic studies of cognitive outcomes. This study also suggests the stability of head circumference correlation with ICV throughout the lifespan.