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Postprediction Inference for Clinical Characteristics Extracted With Machine Learning on Electronic Health Records.

Arjun SondhiAlexander S RichSiruo WangJeffery T Leek
Published in: JCO clinical cancer informatics (2023)
We describe and evaluate methods for fitting statistical models using ML-extracted variables subject to model error. We show that estimation and inference is generally valid when using extracted data from high-performing ML models. More complex methods that incorporate auxiliary labeled data provide further improvements.
Keyphrases
  • electronic health record
  • machine learning
  • clinical decision support
  • big data
  • single cell
  • adverse drug
  • artificial intelligence
  • pet imaging
  • deep learning
  • finite element