Genetic Risk Score for Plasma Uric Acid Levels Is Associated With Early Rapid Kidney Function Decline in Type 2 Diabetes.
Resham Lal GurungM YiamunaaJian-Jun LiuRajkumar DorajooJiexun WangLing WangSylvia LiuClara ChanKeven AngYi-Ming ShaoTavintharan SubramaniamWern E TangChee Fang SumJian-Jun LiuJian-Jun LiuPublished in: The Journal of clinical endocrinology and metabolism (2022)
Elevated plasma UA is an independent risk factor for incident CKD. Furthermore, plasma UA potentially has a causal role in early eGFR loss in T2D patients.
Keyphrases
- uric acid
- type diabetes
- end stage renal disease
- chronic kidney disease
- small cell lung cancer
- metabolic syndrome
- cardiovascular disease
- ejection fraction
- newly diagnosed
- prognostic factors
- epidermal growth factor receptor
- peritoneal dialysis
- insulin resistance
- genome wide
- weight loss
- copy number
- sensitive detection