Chromosomal aberrations and CNVs in twin fetuses with cardiovascular anomalies: Comparison between monochorionic diamniotic and dichorionic diamniotic twins.

Yi ZhangLinhuan HuangXuan HuangZhiming HeShao-Bin LinYe WangLin Li Yanmin LuoQun Fang

Published in: Prenatal diagnosis (2018)

Most of cardiovascular anomalies were identified in one fetus of a twin pair no matter in MCDA or DCDA twin. Primary cardiac structural defects were more common in DCDA group. Monozygotic twins may have discordant phenotypes, karyotypes, and CNVs between 2 fetuses of each pair.

Keyphrases

gestational age
copy number
left ventricular
heart failure
gene expression
dna methylation
genome wide