MSCs derived from amniotic fluid and umbilical cord require different administration schemes and exert different curative effects on different tissues in rats with CLP-induced sepsis.

Rui ChenYingjun XieXuan ZhongFei ChenYu GongNa WangDing Wang

Published in: Stem cell research & therapy (2021)

Our studies suggest the safety and efficacy of AF-MSCs and UC-MSCs in the treatment of CLP-induced sepsis in rats and show that the cells potentially exert different curative effects on the main sepsis-affected tissues.

Keyphrases

umbilical cord
mesenchymal stem cells
acute kidney injury
septic shock
intensive care unit
high glucose
diabetic rats
gene expression
induced apoptosis
bone marrow
atrial fibrillation
drug induced
cell cycle arrest
prognostic factors
cell proliferation
case control
pi k akt