Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells.
Nihal AlMuraikhiDalia AliRadhakrishnan VishnubalajiMuthurangan ManikandanMuhammad AtteyaAbdulaziz SiyalMusaad AlfayezAbdullah AldahmashMoustapha KassemNehad M AlajezPublished in: Stem cells international (2019)
We identified γ-secretase inhibitor (LY411575) as a potent regulator of osteoblastic differentiation of hBMSC that may be useful as a therapeutic option for treating conditions associated with ectopic bone formation.