The association between klotho and kidney and cardiovascular outcomes: a comprehensive systematic review and meta-analysis.

Mehmet KanbayCrischentian BrinzaLasin OzbekMustafa GuldanUluman SismanSidar CopurAndreea CovicDragos-Viorel ScripcariuAlexandru BurlacuAdrian Covic

Published in: Clinical kidney journal (2024)

Lower serum klotho levels serve as a significant predictor of adverse outcomes, including increased risks of all-cause mortality, cardiovascular mortality and progression to end-stage kidney disease among CKD patients.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
peritoneal dialysis
type diabetes
risk factors
risk assessment
patient reported outcomes
climate change
patient reported