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Delusions of love and passion in the behavioral variant of frontotemporal dementia.

Miguel Restrepo-MartinezJesús Ramírez-BermúdezIsis SoKristy ColemanElizabeth Finger
Published in: Neurocase (2024)
Erotomania (de Clérambault's syndrome) refers to the delusional belief that another person, usually socially unreachable, is in love with the holder of the delusion. The occurrence of erotomania in Frontotemporal Dementia has rarely been reported. We present the unique case of a 59-year-old woman with a strong family history of early-onset dementia in whom erotomania was the initial manifestation that led to a diagnosis of definite Behavioral Variant of Frontotemporal Dementia with a pathogenic missense mutation in the MAPT gene. Based on this case, we propose a hypothetical model for developing erotomania in patients with FTD.
Keyphrases
  • early onset
  • late onset
  • risk assessment
  • genome wide
  • intellectual disability
  • cognitive impairment
  • copy number
  • gene expression
  • case report
  • dna methylation
  • autism spectrum disorder
  • genome wide analysis