The lupus anticoagulant titer is associated with elevated antiphosphatidylserine/prothrombin immunoglobulin-M isotype antibody levels.

Abdulrahman SaadallaDong ChenMelissa StuartRajiv K PruthiNahla HeikalMelissa SnyderAneel AshraniJansen Seheult

Published in: International journal of laboratory hematology (2024)

The degree of prolongation of the APTT/DRVVT screening time is not correlated with the LAC titer. Only aPS/PT IgM antibodies levels were strongly correlated with the LAC titers. Additional studies are warranted to determine clinical implications of high LAC titers.

Keyphrases

systemic lupus erythematosus
atrial fibrillation
venous thromboembolism
disease activity