Association of Depression Symptoms and Biomarkers of Risk on Clinical Outcomes in HFrEF.
Andrew SherwoodJames A BlumenthalRobert J MentzGary G KochJoseph G RogersPatricia P ChangChristopher ChienKirkwood F AdamsLisa J Rose-JonesBrian C JensenKristy S JohnsonAlan L HinderliterPublished in: medRxiv : the preprint server for health sciences (2023)
This study underscores the importance of elevated depression symptoms and their association with an increased likelihood of adverse clinical outcomes in patients with HFrEF. Health behaviors may play a greater role than direct biobehavioral pathways in the adverse effects of depression on the HF disease trajectory and resultant clinical outcomes.