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Novel confocal Raman microscopy method to investigate hydration mechanisms in human skin.

Hequn WangQihong ZhangGuangru MaoOscar ConroyYelena PyatskiMichael J FevolaGabriela Oana CulaPrithwiraj MaitraRichard MendelsohnCarol R Flach
Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2019)
Unique information regarding hydration mechanisms are obtained from CRM experiments using D2 O as a probe. The source and relative rates of hydration can be delineated using ex vivo skin with D2 O underneath. One can envision comparing these depth-dependent rates in the presence and absence of topically applied hydrating agents to obtain mechanistic information.
Keyphrases
  • optical coherence tomography
  • health information
  • raman spectroscopy
  • high resolution
  • high throughput
  • soft tissue
  • quantum dots
  • healthcare
  • mass spectrometry
  • single cell
  • fluorescent probe