16S rDNA Sequencing for Bacterial Identification in Preterm Infants with Suspected Early-Onset Neonatal Sepsis.

Sergio I Agudelo A Melissa MorenoJuliana Martínez-GarroJorge Emilio Salazar FlórezRuth LopezMateo Perdigón Ronald Guillermo Peláez Sánchez

Published in: Tropical medicine and infectious disease (2024)

Amplifying the 16S rDNA variable region through PCR and subsequent Sanger sequencing in preterm neonates with suspected early-onset neonatal sepsis can enhance the identification of microbial species that cause infection, especially in negative cultures.

Keyphrases

early onset
low birth weight
preterm infants
late onset
acute kidney injury
septic shock
pulmonary embolism
intensive care unit
single cell
bioinformatics analysis
preterm birth
microbial community
gestational age
genetic diversity