Fibrin supports subcutaneous neonatal porcine islet transplantation without the need for pre-vascularization.
Bassem F SalamaKaren L SeebergerGregory S KorbuttPublished in: Xenotransplantation (2019)
Fibrin matrix facilitates engraftment of NPIs in the subcutaneous site of diabetic mice. These data support further investigation of the subcutaneous site for clinical islet xenotransplantation.