The optimisation of noninvasive ventilation in amyotrophic lateral sclerosis: a systematic review.

David O'Brien Theocharis Stavroulakis Susan Kathryn Baxter Paul Norman Stephen M Bianchi Mark Elliott Maxine Johnson Mark Clowes Aldara Garcia-Sánchez Esther V Hobson Christopher J McDermott

Published in: The European respiratory journal (2019)

This review highlights that NIV optimisation requires an individualised approach to respiratory management tailored to the differing needs of each patient. Ultimately, this should lead to improved survival and quality of life. This review expands on recommendations in current international guidelines for NIV use in ALS and identifies areas for future research.

Keyphrases

clinical practice
gene expression
intensive care unit
amyotrophic lateral sclerosis
mechanical ventilation
free survival