Membrane attack complex (C5b-9 complex or Mac), is strongly present in lesional skin from patients with endemic pemphigus foliaceus in El Bagre, Colombia.
Ana Maria Abreu VelezYulieth A Upegui-ZapataCarlos A Valencia-YepesEduardo Upegui-QuicenoNatalia-Regina Mesa-HerreraAlejandra M Jiménez-EchavarriaCésar D N PulidoBruce R SmollerMichael S HowardPublished in: Journal of cutaneous pathology (2019)
Patients affected by El Bagre-EPF have lesional deposition of complement/C5b, which correlates with disease severity and previously established serologies.