Smart thermosensitive chitosan hydrogel for nasal delivery of ibuprofen to treat neurological disorders.

Hanieh GholizadehShaokoon ChengMichele PozzoliElisa MesserottiDaniela TrainiPaul YoungAgisilaos KourmatzisHui Xin Ong

Published in: Expert opinion on drug delivery (2019)

A thermosensitive CS-based formulation has been successfully developed with suitable rheological properties, aerosol performance and biological properties that is beneficial for nose-to-brain drug delivery.

Keyphrases

drug delivery
cancer therapy
drug release
white matter
resting state
wound healing
functional connectivity
water soluble
multiple sclerosis
subarachnoid hemorrhage