Causes and attributable fraction of death from ARDS in inflammatory phenotypes of sepsis.
Bruno EvrardPratik SinhaKevin DelucchiCarolyn M HendricksonKirsten N KangelarisKathleen D LiuAndrew WillmoreNelson WuLucile NeytonEmma SchmiegeAntonio GomezV Eric KerchbergerAnn ZaluckyMichael A MatthayLorraine B WareCarolyn S CalfeePublished in: Critical care (London, England) (2024)
is modest in both phenotypes whereas primary cause of death among patients with sepsis differed substantially by phenotype. This study identifies challenges in powering future clinical trials to detect changes in mortality outcomes among patients with sepsis and ARDS.