Development of a bisphenol A based chemosensor for Al 3+ and its application in cell imaging and plant root imaging.
Sibshankar BariDinesh MaityDeepanjan MridhaTarit RoychowdhuryPritam GhoshPartha RoyPublished in: Analytical methods : advancing methods and applications (2024)
Bisphenol A is a fluorophoric platform that is used to develop chemosensors for various species. Herein, we report a bisphenol A based Schiff-base molecule, 4,4'-(propane-2,2-diyl)bis(2-(( E )-((2-hydroxy-5-methylphenyl)imino)methyl)phenol) (Me-H 4 L), as a selective chemosensor for Al 3+ . Among the several metal ions, it shows a significant increment in its fluorescence intensity (50 fold) at 535 nm in the presence of Al 3+ ions. The enhanced fluorescence was attributed to the CHEFF mechanism and inhibition of CN isomerization. The limit of detection value of Me-H 4 L for Al 3+ was determined to be 9.65 μM. Its quantum yield and lifetime increased considerably in the presence of the cation. Some theoretical calculations were performed to explain the interaction between Al 3+ and the probe. Furthermore, Me-H 4 L was applied in cell imaging studies using animal cells and plant roots.
Keyphrases
- high resolution
- single cell
- quantum dots
- molecular dynamics
- cell therapy
- induced apoptosis
- aqueous solution
- ionic liquid
- photodynamic therapy
- living cells
- oxidative stress
- high intensity
- cell proliferation
- density functional theory
- signaling pathway
- cell cycle arrest
- sensitive detection
- case control
- genetic diversity