Ex Vivo Intact Tissue Analysis Reveals Alternative Calcium-sensing Behaviors in Parathyroid Adenomas.

James Koh Run Zhang Sanziana A Roman Quan-Yang Duh Jessica Gosnell Wen Shen Insoo Suh Julie Ann Sosa

Published in: The Journal of clinical endocrinology and metabolism (2021)

Calcium-sensing capacity varies among parathyroid tumors but downregulation of the calcium-sensing receptor (CASR) is not an obligate underlying mechanism. Differences in tumor calcium responsiveness may contribute to variations in PHPT clinical presentation.

Keyphrases

binding protein