Association between the hypokalaemia index based on area over the serum potassium concentration curve and occurrence of acute kidney injury in patients administered liposomal amphotericin B.

Takashi UedaKazuhiko NakajimaKaoru IchikiKaori IshikawaKumiko YamadaToshie TsuchidaNaruhito OtaniShingo TakuboKosuke IijimaMotoi UchinoYuki HorioRyuichi KuwaharaTakeshi KimuraYasushi MurakamiYasuhiro NozakiSoichiro NakamaYoshitsugu MiyazakiYoshio Takesue

Published in: Mycoses (2024)

A ≥ 10% decrease in the K concentration was a significant factor for AKI in patients receiving L-AMB therapy. In such patients, dose reduction or alternative antifungals could be considered based on the hypokalaemia index.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
acute kidney injury
stem cells
patient reported
cell therapy