Fibroblast growth factor 23-Klotho and mineral metabolism in the first year after pediatric kidney transplantation: A single-center prospective study.
Mai KubotaYuko HamasakiJunya HashimotoYujiro AokiTakeshi KawamuraAkinobu SaitoRena YuasaMasaki MuramatsuHirotaka KomabaMasao ToyodaMasafumi FukagawaSeichiro ShishidoKen SakaiPublished in: Pediatric transplantation (2022)
FGF23 in pediatric kidney transplant patients decreased rapidly after transplantation and associated with post-transplant hypophosphatemia and increased phosphorus excretion. Post-transplant αKlotho was low early post-transplant but tended to increase subsequently. Post-transplant αKlotho was unaffected by pre-transplant FGF23 or other factors, suggesting pre-transplant chronic kidney disease status has no effect.