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Fibroblast growth factor 23-Klotho and mineral metabolism in the first year after pediatric kidney transplantation: A single-center prospective study.

Mai KubotaYuko HamasakiJunya HashimotoYujiro AokiTakeshi KawamuraAkinobu SaitoRena YuasaMasaki MuramatsuHirotaka KomabaMasao ToyodaMasafumi FukagawaSeichiro ShishidoKen Sakai
Published in: Pediatric transplantation (2022)
FGF23 in pediatric kidney transplant patients decreased rapidly after transplantation and associated with post-transplant hypophosphatemia and increased phosphorus excretion. Post-transplant αKlotho was low early post-transplant but tended to increase subsequently. Post-transplant αKlotho was unaffected by pre-transplant FGF23 or other factors, suggesting pre-transplant chronic kidney disease status has no effect.
Keyphrases
  • end stage renal disease
  • chronic kidney disease
  • kidney transplantation
  • peritoneal dialysis
  • newly diagnosed
  • ejection fraction
  • prognostic factors
  • stem cells
  • cell therapy
  • risk assessment
  • bone marrow
  • heavy metals