The potential use of serum interleukin-21 as biomarker for lupus nephritis activity compared to cytokines of the tumor necrosis factor (TNF) family.

Hend ShaterMary Wadie FawzyAlyaa FaridAzza El-AmirSalwa FouadNeveen Madbouly

Published in: Lupus (2022)

For Egyptian SLE patients, serum levels of IL-21 were superior to TNF-SF13 and BlyS and correlated significantly with the activity indexes of LN, indicating a promising role as a potential biomarker of active LN.

Keyphrases

rheumatoid arthritis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
systemic lupus erythematosus
disease activity
prognostic factors
peritoneal dialysis