Indium-111 radiolabelling of a brain-penetrant Aβ antibody for SPECT imaging.
Tobias GustavssonMatthias M HerthDag SehlinStina Syvänen
Published in: Upsala journal of medical sciences (2024)
In]biAb in bone marrow and intracellular accumulation in brain tissue indicated some off-target interactions or potential interaction with intrabrain TfR resulting in a relatively high non-specific background signal.