A Predictive Tool Based on DNA Methylation Data for Personalized Weight Loss through Different Dietary Strategies: A Pilot Study.
Nereyda Carolina García-ÁlvarezJosé-Ignacio Riezu-BojJosé Alfredo Martínez HernándezSonia García-CalzónFermin Ignacio MilagroPublished in: Nutrients (2023)
Overall, DNA methylation predicts the %BMIL of two 4-month hypocaloric diets and was able to determine which type of diet is the most appropriate for each individual. The results of this pioneer study confirm that epigenetic biomarkers may be further used for precision nutrition and the design of personalized dietary strategies against obesity.
Keyphrases
- weight loss
- dna methylation
- bariatric surgery
- roux en y gastric bypass
- gene expression
- genome wide
- gastric bypass
- physical activity
- glycemic control
- weight gain
- type diabetes
- insulin resistance
- electronic health record
- obese patients
- copy number
- skeletal muscle
- machine learning
- high fat diet induced
- deep learning
- data analysis