Potentiation of Imipramine-Induced Anti-hyperalgesic and Anti-Nociceptive Effects by Citicoline in the Sciatic Nerve Ligated Mice.

Negar Raissi-DehkordiNastaran Raissi-DehkordiBardia HajikarimlooFatemeh KhakpaiMohammad-Reza Zarrindast

Published in: Archives of Iranian medicine (2024)

Therefore, it can be concluded that citicoline (as an adjuvant substance) enhanced the efficacy of imipramine for the modulation of pain behavior in nerve-ligated mice.

Keyphrases

high fat diet induced
neuropathic pain
chronic pain
early stage
high glucose
diabetic rats
type diabetes
wild type
insulin resistance
endothelial cells
oxidative stress
skeletal muscle
stress induced