Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease.
Nathalie H P ClaessensSelma O AlgraTom L OuwehandNicolaas J G JansenRenske SchappinFelix HaasMaria J C EijsermansLinda S de VriesManon J N L Bendersnull nullPublished in: Developmental medicine and child neurology (2018)
This paper extends knowledge about neonatal brain injury and long-term outcome in congenital heart disease. Children with white matter injury show lower IQ and more attention problems at school age. Injury of the posterior limb of the internal capsule increases the risk of motor problems. This study provides evidence for worse outcomes in neonates acquiring brain injury around cardiac surgery.