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Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production.
Parisa Moradbeigi
Sara Hosseini
Mohammad Salehi
Asghar Mogheiseh
Published in:
Biological procedures online (2024)
Overall, this study highlights the significant potential of the MBCD-SMGE technique for generating targeted mutant mice. It holds enormous promise for modeling human diseases and improving desirable traits in animals.
Keyphrases
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wild type
endothelial cells
cancer therapy
genome wide
high fat diet induced
ionic liquid
gene expression
adipose tissue
metabolic syndrome
dna methylation
climate change
mass spectrometry
insulin resistance
artificial intelligence
capillary electrophoresis