Acute kidney injury requiring kidney replacement therapy in childhood lupus nephritis: a cohort study of the Pediatric Nephrology Research Consortium and Childhood Arthritis and Rheumatology Research Alliance.

Brian R StotterEllen CodyHongjie GuAnkana DagaLarry A GreenbaumMinh Dien DuongAlexandra MazoBeatrice GoilavAlexis BoneparthMahmoud KallashAhmed ZeidWacharee SeeherunvongRebecca R ScobellIssa AlhamoudCaitlin E CarterSiddharth ShahCaroline E StraatmannBradley P DixonJennifer C CooperRaoul D NelsonDeborah M LevyHermine I BrunnerPriya S VergheseScott E Wenderfer

Published in: Pediatric nephrology (Berlin, Germany) (2022)

Children with LN and AKI stage 3D have a high long-term risk of kidney failure. Severe tubular atrophy and interstitial fibrosis at the time of AKI, but not AKI duration, are predictive of kidney disease progression. A higher resolution version of the Graphical abstract is available as Supplementary information.

Keyphrases

acute kidney injury
replacement therapy
cardiac surgery
childhood cancer
rheumatoid arthritis
smoking cessation
young adults
early life
health information
single molecule
healthcare
endothelial cells
social media
psychometric properties