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Acute kidney injury requiring kidney replacement therapy in childhood lupus nephritis: a cohort study of the Pediatric Nephrology Research Consortium and Childhood Arthritis and Rheumatology Research Alliance.

Brian R StotterEllen CodyHongjie GuAnkana DagaLarry A GreenbaumMinh Dien DuongAlexandra MazoBeatrice GoilavAlexis BoneparthMahmoud KallashAhmed ZeidWacharee SeeherunvongRebecca R ScobellIssa AlhamoudCaitlin E CarterSiddharth ShahCaroline E StraatmannBradley P DixonJennifer C CooperRaoul D NelsonDeborah M LevyHermine I BrunnerPriya S VergheseScott E Wenderfer
Published in: Pediatric nephrology (Berlin, Germany) (2022)
Children with LN and AKI stage 3D have a high long-term risk of kidney failure. Severe tubular atrophy and interstitial fibrosis at the time of AKI, but not AKI duration, are predictive of kidney disease progression. A higher resolution version of the Graphical abstract is available as Supplementary information.
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