Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Guoqiang YangJiraporn KantapanMaryam MazharXue BaiYuanxia ZouHonglian WangBingfeng HuangSijing YangNathupakorn DechsupaWang LiPublished in: Stem cell research & therapy (2023)
These data suggested that the combined treatment exerts a collaborative effect in alleviating ICH-induced inflammatory response through the downregulation of the Mincle/syk signaling pathway following ICH, further improving the neurologic deficits and brain edema.
Keyphrases
- signaling pathway
- inflammatory response
- mesenchymal stem cells
- diabetic rats
- high glucose
- oxidative stress
- pi k akt
- tyrosine kinase
- epithelial mesenchymal transition
- traumatic brain injury
- cell proliferation
- induced apoptosis
- cell therapy
- quality improvement
- stem cells
- immune response
- combination therapy
- endoplasmic reticulum stress
- lps induced
- multiple sclerosis
- data analysis
- cerebral ischemia