Amyloid-β PET-Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic.

Ebba Gløersen MüllerTrine Holt EdwinCaroline StokkeSigrid Stensby NavelsakerAlmira BabovicNenad BogdanovicAnne-Brita KnapskogMona Elisabeth Revheim

Published in: PloS one (2019)

The present study showed an excellent correlation of Aβ42 in CSF and 18F-Flutemetamol PET and the presented cut-off value for Aβ42 yields high sensitivity and specificity for 18F-Flutemetamol PET. 18F-Flutemetamol PET was the best predictor of clinical AD diagnosis.

Keyphrases

pet ct
positron emission tomography
computed tomography
cerebrospinal fluid
pet imaging
primary care
working memory
cognitive decline