Tirzepatide 10 and 15 mg compared with semaglutide 2.4 mg for the treatment of obesity: An indirect treatment comparison.

Carel W le RouxEmily R HankoskyDuzhe WangRaleigh E MalikMaria YuAna HickeyHong KanMathijs C BunckAdam StefanskiLuis-Emilio Garcia-Perez Sean Wharton

Published in: Diabetes, obesity & metabolism (2023)

Currently there are no direct comparisons of tirzepatide and semaglutide for weight management. Using the matching-adjusted indirect treatment comparison method to compare the efficacy of tirzepatide and semaglutide for chronic weight management, this analysis showed greater weight loss with tirzepatide 10 and 15 mg versus semaglutide 2.4 mg.

Keyphrases

weight loss
type diabetes
body mass index
physical activity
weight gain
adipose tissue
roux en y gastric bypass
combination therapy
data analysis