Login / Signup

Proliferation, Migration, and ECM Formation Potential of Human Annulus Fibrosus Cells Is Independent of Degeneration Status.

Sylvia HondkeMario CabrajaJan Philipp KrügerStefan StichTony HartwigMichael SittingerMichaela Endres
Published in: Cartilage (2018)
Our study demonstrated that AF cells retain their potential for proliferation, migration, and ECM formation independent of the degeneration status of the tissue. Proliferation, migration, and ECM synthesis of the endogenous AF cells can be supported by different supplements. Hence, endogenous AF cells might be a suitable cell source for a regenerative repair approaches.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • signaling pathway
  • stem cells
  • endothelial cells
  • endoplasmic reticulum stress
  • cell death
  • risk assessment
  • pi k akt
  • aortic valve
  • climate change
  • induced pluripotent stem cells