Review of Case Narratives from Fatal Overdoses Associated with Injectable Naltrexone for Opioid Dependence.
Roxanne SaucierDaniel WolfeNabarun DasguptaPublished in: Drug safety (2019)
Vivitrol adverse event reports suggest the need to investigate two months following the last medicine injection as a period of particular concern for overdose. A registry study would best quantify risk. Providers should report suspected post-discontinuation overdoses to government authorities.