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Role of the HLA-G regulatory region polymorphisms in idiopathic recurrent spontaneous abortions (RSA).

Binata MarikKhusru NomaniNutan AgarwalVatsla DadhwalArundhati Sharma
Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2023)
The study indicates a protective role of the CC genotypes of the two HLA-G 5'-URR polymorphisms, -762C/T and -477C/G, against RSA. It also suggests that women with the 14 bp deletion/insertion genotype have a significantly higher risk of RSA.
Keyphrases
  • transcription factor