Novel cell culture system for monitoring cells during continuous and variable negative-pressure wound therapy.

Toshifumi YamashiroToshihiro KushibikiYoshine MayumiMasato TsuchiyaMiya IshiharaRyuichi Azuma

Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2023)

We developed a negative-pressure cell culture device that enables negative-pressure cell culture under conditions similar to those used in clinical practice and is able to monitor cells under NPWT. Further experiments using this device would provide high-quality molecular biological evidence for NPWT.

Keyphrases

induced apoptosis
cell cycle arrest
clinical practice
endoplasmic reticulum stress
oxidative stress
stem cells
mesenchymal stem cells
single molecule
pi k akt