Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.

Hong JiangDong Ho Shin Teresa T Nguyen Juan FueyoXuejun FanVerlene HenryCaroline C CarrilloYanhua YiMarta Marija AlonsoTiara L CollierYing YuanFrederick F LangCandelaria Gomez-Manzano

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Localized intratumoral injection of Delta-24-RGDOX induces an in situ antovaccination of the treated melanoma, the effect of which changes the immune landscape of the treated mice, resulting in systemic immunity against disseminated s.c. and i.c. tumors.

Keyphrases

newly diagnosed
single cell
ultrasound guided
drug induced
adipose tissue
skeletal muscle