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Intra-Articular Injections of Curcumin Monoglucuronide TBP1901 Suppresses Articular Cartilage Damage and Regulates Subchondral Bone Alteration in an Osteoarthritis Rat Model.

Akihiro NakahataAkira ItoRyo NakaharaAtsuhiro KishimotoAtsushi ImaizumiTadashi HashimotoShogo MukaiYasuaki NakagawaHiroshi Kuroki
Published in: Cartilage (2021)
TBP1901 intra-articular injections suppressed synovial inflammation in the acute phase of PTOA in DMM rats. In the chronic phase, TBP1901 suppresses articular cartilage damage and regulates SB plate changes.
Keyphrases
  • oxidative stress
  • signaling pathway
  • platelet rich plasma
  • ultrasound guided
  • rheumatoid arthritis
  • bone mineral density
  • knee osteoarthritis
  • postmenopausal women
  • body composition
  • bone loss