The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex.

Takeshi TsusakaKei FukudaChikako ShimuraMasaki KatoYoichi Shinkai

Published in: Epigenetics & chromatin (2020)

Our findings contributed to further understanding the function of ATF7IP in the SETDB1 complex, revealed the role of the FNIII domain of ATF7IP in transcriptional silencing, and suggested a potential underlying molecular mechanism for it.

Keyphrases

type iii
transcription factor
endoplasmic reticulum stress
gene expression
heat shock
single cell
climate change