The risk of late effects following pediatric and adult radiotherapy regimens in Hodgkin lymphoma.
Anni Young LundgaardLisa Lyngsie HjalgrimLaura Ann RechnerMichael LundemannN Patrik BrodinMorten JoergensenLena SpechtMaja Vestmoe MaraldoPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2020)
Pediatric regimens selected patients with more advanced disease to radiotherapy resulting in larger target volumes and higher doses to the OARs. Target volume rather than prescribed dose impacted OAR exposure. Consequently, the estimated risk of radiation-induced late effects and corresponding LYL was increased when compared to adult regimens.