Using a gene expression signature when controversy exists regarding the indication for adjuvant systemic treatment reduces the proportion of patients receiving adjuvant chemotherapy: a nationwide study.
Anne KuijerA C M van BommelC A DrukkerM van der Heiden-van der LooC H SmorenburgPieter J WestenendS C LinnE J Th RutgersS G EliasTh van DalenPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2015)
In patients in whom the Dutch national guidelines suggest the use of a gene-expression profile, 70-GS use is associated with a 10% decrease in the administration of adjuvant CT.Genet Med 18 7, 720-726.Genetics in Medicine (2016); 18 7, 720-726. doi:10.1038/gim.2015.152.