A comparison of the metabolic side-effects of the second-generation antipsychotic drugs risperidone and paliperidone in animal models.
Heidi N BoydaRic M ProcyshynLurdes TseJessica W Y YuenWilliam G HonerAlasdair M BarrPublished in: PloS one (2021)
In preclinical models, both risperidone and paliperidone exhibited notable metabolic side-effects that were dose-dependent. Differences between the two were modest, and most notable as effects on fasting glucose.