An application of the Toronto Childhood Cancer Stage Guidelines in three population-based cancer registries: The case of central nervous tumors.
Carlotta SacerdoteMaria Luisa MossoDaniela AlessiFranco MerlettiGiovanna TagliabueAnna D'AgostinoSabrina FabianoFabio SavoiaPatrizia PigaMarcella SessaFrancesco VetranoGemma GattaMilena MaulePublished in: Pediatric blood & cancer (2020)
The use of the Toronto Childhood Cancer Stage Guidelines is feasible for staging medulloblastoma in Italian population-based cancer registries, whereas it is more difficult for ependymomas. In Italy, cerebrospinal fluid examination, one of the decisive tests to stage CNS tumors, is not routinely performed as a first-line diagnosis procedure in ependymoma pediatric patients. A similar exercise by a larger number of cancer registries in different countries could suggest improvements in the childhood cancer staging system.