TINU: A Multisystemic Inflammatory Disorder-Case Report and Literature Review.
Juan Montejo-HernándezJorge Rico-FontalvoJosé CabralesShuchi AnandMaría Cristina Martínez-ÁvilaClaudia Duran-MerinoLuis Arias-RestrepoCamilo Andrés Gómez DuranPublished in: Case reports in nephrology (2024)
Background . The syndrome of tubulointerstitial nephritis and uveitis (TINU) is a rare oculorenal condition, mainly seen in children and women. The underlying cause of this disease is unknown. Case Presentation . We report a 24-year-old male without any past medical history, diagnosed with bilateral uveitis and azotemia. Biopsy revealed tubulointerstitial nephritis, consistent with TINU syndrome. Fluorescein angiogram revealed peripheral retinal vasculitis. Discussion . TINU is a rare disorder that needs to be distinguished from sarcoidosis, Sjogren's disease, and tuberculosis. Treatment is indicated in patients with progressive renal insufficiency, consisting of steroid therapy. Most patients recover kidney function. Its early recognition is important to offer the best chance of organ preservation.
Keyphrases
- case report
- end stage renal disease
- juvenile idiopathic arthritis
- ankylosing spondylitis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- single cell
- healthcare
- multiple sclerosis
- mycobacterium tuberculosis
- young adults
- stem cells
- optical coherence tomography
- polycystic ovary syndrome
- oxidative stress
- patient reported outcomes
- pregnant women
- type diabetes
- ultrasound guided
- adipose tissue
- rheumatoid arthritis
- systemic lupus erythematosus
- pregnancy outcomes
- insulin resistance
- replacement therapy
- combination therapy
- patient reported
- smoking cessation