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Flavonoids isolated from the South African weed Chromolaena odorata (Asteraceae) have pharmacological activity against uropathogens.

Aitebiremen G Omokhua-UyiMuna A AbdallaCarmen M LeonardAbimbola AroOsariyekemwen O UyiJohannes Van StadenLyndy J McGaw
Published in: BMC complementary medicine and therapies (2020)
Pharmacological activities displayed by compounds 2 and 3 isolated from C. odorata and low toxicity recorded credits it as a potential lead for the development of useful prophylactic treatments and anti-infective drugs against UTIs. Although known compounds, this is the first time these compounds have been isolated from the South African weed C. odorata and tested for antimicrobial, anti-biofilm, metabolic inhibition and anti-adhesion activities.
Keyphrases
  • staphylococcus aureus
  • pseudomonas aeruginosa
  • biofilm formation
  • oxidative stress
  • escherichia coli
  • candida albicans
  • climate change