Open-Label, Multicenter, Randomized, Biomarker-Integrated Umbrella Trial for Second-Line Treatment of Advanced Gastric Cancer: K-Umbrella Gastric Cancer Study.
Choong-Kun LeeHyo Song KimMinkyu JungHyunki KimWoo Kyun BaeDong-Hoe KooHei Cheul JeungSook Ryun ParkIn Gyu HwangDae Young ZangHyun Woo LeeSejung ParkChung-Mo NamHyun Cheol ChungSun Young RhaPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Although biomarker group did not show better survival than the control group, IHC-based screening and allocation of patients with AGC to the second-line treatment in an umbrella design were feasible for effective early screening of novel agents.