Novel circular RNA circSOBP governs amoeboid migration through the regulation of the miR-141-3p/MYPT1/p-MLC2 axis in prostate cancer.

Fan ChaoZhenyu SongShiyu WangZhe MaZhiyuan ZhuoTing MengGuoxiong Xu Gang Chen

Published in: Clinical and translational medicine (2022)

Our results suggest that circSOBP suppresses amoeboid migration of PCa cells and inhibits migration and invasion through sponging miR-141-3p and regulating the MYPT1/p-MLC2 axis.

Keyphrases

prostate cancer
induced apoptosis
cell cycle arrest
signaling pathway
radical prostatectomy
cell death
oxidative stress