miR-27b-5p inhibits BeWo cells fusion by regulating WNT2B and enzyme involved in progesterone synthesis.

Satish Kumar GuptaRicha MishraAnkita MalikPiyush ChaudharySudha Saryu MalhotraAmulya K PandaSatish Kumar Gupta

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2021)

These observations suggest that reduced miR-27b-5p in forskolin-treated BeWo cells leads to increased secretion of progesterone and hCG due to loss of repressional control on HSD3β1 and WNT2B.

Keyphrases

induced apoptosis
cell cycle arrest
stem cells
cell proliferation
signaling pathway
cell death
oxidative stress