Site-Specific Cross-Linking of Galectin-1 Homodimers via Poly(ethylene glycol) Bismaleimide.

Bryant J KaneMargaret M FettisShaheen A FarhadiRenjie LiuGregory A Hudalla

Published in: Cellular and molecular bioengineering (2021)

Collectively, these data demonstrate that thiol-Michael addition bioconjugation leads to a PEG-cross-linked Gal1 homodimer with improved extracellular signaling activity that does not require a reducing environment to be functional.

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