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Alternative polyadenylation produces multiple 3' untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons.

Mohamed DoulazmiCyril CrosIsabelle DusartAlain TrembleauCaroline Dubacq
Published in: BMC genomics (2019)
We demonstrated for the first time that odorant receptor genes are extensively subject to alternative polyadenylation. This ground-breaking change to the landscape of 3'UTR isoforms of Olfr mRNAs opens new avenues for investigating their respective functions, especially during the differentiation of olfactory sensory neurons.
Keyphrases
  • spinal cord
  • genome wide analysis
  • multidrug resistant
  • binding protein